Dutasteride Avodart CAS 164656-23-9 for Anti Hair Loss Treatment 1. Product Name:Dutasteride 2. Synonyms: (5alpha, 17beta)-n-{2, 5-bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-l-ene-17-carboxamide; DUTASTERIDE; (5A, 17)-N-[2, 5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide; Avodart; GI 198745 3. CAS: 164656-23-9 4. MF: C27H30F6N2O2 5. MW: 528.53 6. Assay: 99% 7. Color: white Powder Read More

Dutasteride Avodart CAS 164656-23-9 for Anti Hair Loss Treatment

1. Product Name:Dutasteride
2. Synonyms: (5alpha, 17beta)-n-{2, 5-bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-l-ene-17-carboxamide; DUTASTERIDE; (5A, 17)-N-[2, 5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide; Avodart; GI 198745
3. CAS: 164656-23-9
4. MF: C27H30F6N2O2
5. MW: 528.53
6. Assay: 99%
7. Color: white Powder
8. Usage: treatment for hair loss

Dutasteride Description:

1. Dutasteride useful for the symptoms of benign prostatic hyperplasia (BPH); colloquially known as an “enlarged prostate”.

2. In those who are being regularly screened 5-alpha-reductase inhibitor (finasteride and dutasteride) reduce the overall risk of being diagnosed with prostate cancer however there is insufficient data to determine if they have an effect on the risk of death and may increase the chance of more serious cases.

3. This class of medications increases rates of erectile dysfunction (with between 5% and 9% developing problems after starting their use). This is linked to lower quality of life and can cause stress in relationships. There is also an association with lowered sexual desire. It has been reported that these adverse sexual side effects may persist even after discontinuation of the drug.

4. The FDA has added a warning to dutasteride about an increased risk of high-grade prostate cancer. While the potential for positive, negative or neutral changes to the potential risk of developing prostate cancer with dutasteride has not been established, evidence has suggested it may temporarily reduce the growth and prevalence of benign prostate tumors, but could also mask the early detection of prostate cancer.

5. The primary area for concern is for patients who may develop prostate cancer whilst taking dutasteride for benign prostatic hyperplasia, which in turn could delay diagnosis and early treatment of the prostate cancer, thereby potentially increasing the risk of these patients developing high-grade prostate cancer.

Avodart (dutasteride) 500 µg soft capsules

1. Prostate enlargement ,Dutasteride is useful for treating benign prostatic hyperplasia (BPH); colloquially known as an “enlarged prostate”.It is approved by the Food and Drug Administration (FDA) in the U.S. for this indication.

2. Prostate cancer , In those who are being regularly screened, 5α-reductase inhibitors such as finasteride and dutasteride reduce the overall risk of being diagnosed with prostate cancer; however, there is insufficient data to determine if they have an effect on the risk of death and may increase the chance of more serious cases.

3. Pattern hair loss, Dutasteride is approved for the treatment of male androgenetic alopecia in South Korea at a dosage of 0.5 mg per day. It has been found in several studies to improve hair growth in men more rapidly and to a greater extent than 2.5 mg/day finasteride. Dutasteride has also been used off-label in the treatment of female pattern hair loss.

4. Excessive hair growth , Although no reports specific to dutasteride currently exist,5α-reductase inhibitors like finasteride have been found to be effective in the treatment of hirsutism (excessive facial and/or body hair growth) in women.In a study of 89 women with hyperandrogenism due to persistent adrenarche syndrome, finasteride produced a 93% reduction in facial hirsutism and a 73% reduction in bodily hirsutism after 2 years of treatment.Other studies using finasteride for hirsutism have also found it to be clearly effective.Dutasteride may be more effective than finasteride for this indication due to the fact that its inhibition of the 5α-reductase enzyme is comparatively more complete

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