SR9011 sarm Stenabolic 1379686-29-9 white powder
Cas No 1379686-29-9
Molucelar weight 479.03524
Appearance: White powder
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.
Recommended for use in peroxide cured coatings, sealants, and PCV-based plastisols. Performance properties include: good adhesion, good chemical resistance, good hardness, good heat resistance and high abrasion resistance.
what is SR9011 ?
1. SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure.
2. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.
3. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver,
4. skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia.
5. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
How SR9011 works ?
By binding and activating the Rev-Erb supermolecule, Stenabolic triggers a awfully wide selection of processes within the body. the foremost distinguished being the rise of mitochondria count within the muscles ANd an increased metabolism.
As a consequence of the enhanced variety of mitochondria within the muscles, the user can notice a forceful improvement in endurance and muscle strength.
In fact, the mice utilized in studies might run five hundredth additional once they were administered with SR9011, each in terms of distance and time. this can be attainable thanks to the actual fact that these mitochondria area unit exactly those generating energy within the body. Besides, due to the rise in variety of macrophages, defective mitochondria area unit far from the muscles and replaced with new ones.
SR9011 use in bodybuilding
There is no got to be a genius to appreciate all the chances SR9011 opens to associate degree jock – wonderful endurance and strength, fat loss, muscle hypertrophy (growth), improved sterol and glucose levels, associate degreed an augmented metabolism.
Hence, one will expect results like those seen with Cardarine (GW-501516), however with significantly additional further edges. Besides, since stenabolic works nice each solo or stacked, it’ll be a really sensible addition to any steroid or SARMS cycle, and it’ll provide particularly spectacular results once used at the side of Cardarine.
All in all, Stenabolic can permit you to try and do additional cardio coaching, lift more, lose fat, gain lean muscle mass, and improve sterol levels. sterol and cardio management is incredibly necessary once mistreatment SR together with such steroids as Anavar or Trenbolone.
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