Name:Testosterone decanoate powder
CAS Number: 5721-91-5
Appearance: White to almost white crystalline powder
Depot Testosterone is the first long-acting testosterone to be introduced to the market. It’s primary objective is the treatment of male hypogonadism. This is a condition where there is a reduced or absent secretion of testosterone from the testes. Decreased sex drive, erectile dysfunction, muscle loss and weakness and depression are all associated with hypogonadism. There is also an increased risk of developing osteoporosis.
Depot Testosterone is currently available under the brand name NEBIDO. It is designed to be injected every three months. Nebido contains Testosterone Undecanoate as its active ingredient. You may be familiar with this compound as it is also used in the oral steroid Andriol.
How To Take Testosterone Undecanoate
Nebido is injected slowly into the gluteal muscle, where it forms a reservoir of the drug. The compound then gradually releases from the injection site and is cleaved by serum esterases into testosterone and undecanoic acid.
On administration of Nebido serum concentrations of testosterone rapidly increase with notable elevations observed the very next day after injection.
This form of testosterone is also well-tolerated, local irritation being moderate and lasting for no more than three days. Another bonus with this form of testosterone is the fact that – unlike short acting esters- fluctuations in androgen levels are unlikely to be a problem. Hemoglobin and Hematocrit levels – although elevated – remain within the normal range and bone density shows a marked improvement.
Benefit of Testosterone Undecanoate
Well, for a start there is the benefit of less frequent injections. There is also the convenience of steady serum testosterone levels. Depot testosterone (Nebido) also appears to have less influence on blood pressure and a lower tendency towards estrogen conversion. It also seems to have a favorable influence on cholesterol levels with studies reporting a slight decline in total cholesterol in patients who were given this substance.
Dosage Of Testosterone Undecanoate
In medical trials, hypogonadal men were given an initial injection of 750mg Nebido, followed 4 weeks later by an additional 750mg ‘loading’ injection and then 750mg every 10 weeks thereafter. For bodybuilding purposes, there have been reports of competitors injecting anything from 1000 – 3000mg. This would lead to a sustained level of testosterone in the body lasting 10-12 weeks. On top of the testosterone they may add anabolic agents like Deca Durabolin, Equipoise or Trenbolone Acetate.
Nebido is distributed in multi-use vials, each containing 1000mg testosterone Undecanoate in a 4-ml solution for injection (250mg testosterone Undecanoate/ml).
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